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Targeting the proinflammatory cytokines, oxidative stress, apoptosis and TGF-β1/STAT-3 signaling by irbesartan to ameliorate doxorubicin-induced hepatotoxicity

InflammationRedox SignalingAnti-inflammatoryMedicineLiver PhysiologyImmunologyPathologyCell DeathHepatotoxicityReactive Oxygen SpeciePharmacologyCell SignalingDoxorubicin-induced HepatotoxicityDrug-induced Liver InjuryOxidative StressProinflammatory Cytokines