Concepedia

Genetic Characterization of GnRH/LH-Responsive Primary Aldosteronism

Nadia Gagnon, Katia Y Cáceres‐Gorriti, Gilles Corbeil, Nada El Ghoyareb, Natasha Ludwig, Mathieu Latour, André Lacroix, Isabelle Bourdeau

The Journal of Clinical Endocrinology & Metabolism · 2018 · 33 citations · 21 references

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Abstract

Aberrant regulation of aldosterone by GnRH is frequent in PA, but is not often associated with somatic CTNNB1, although it may be found with somatic KCNJ5 mutations.

References

21

The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline

John W. Funder, Robert M. Carey, Franco Mantero et al. · The Journal of Clinical Endocrinology & Metabolism · 2016 · 2.8K citations · Full text

A Prospective Study of the Prevalence of Primary Aldosteronism in 1,125 Hypertensive Patients

Gian Paolo Rossi, Giampaolo Bernini, Chiara Caliumi et al. · Journal of the American College of Cardiology · 2006 · 1.4K citations

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K <sup>+</sup> Channel Mutations in Adrenal Aldosterone-Producing Adenomas and Hereditary Hypertension

Murim Choi, Ute I. Scholl, Peng Yue et al. · Science · 2011 · 962 citations

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Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism

Ute I. Scholl, Gerald Goh, Gabriel Stölting et al. · Nature Genetics · 2013 · 604 citations

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Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension

Felix Beuschlein, Sheerazed Boulkroun, Thomas Wieland et al. · Nature Genetics · 2013 · 552 citations · Full text

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