Concepedia

Bispecific antibodies (anti-mPEG/anti-HER2) for active tumor targeting of docetaxel (DTX)-loaded mPEGylated nanocarriers to enhance the chemotherapeutic efficacy of HER2-overexpressing tumors

Chia-Yu Su, Michael Chen, Ling-Chun Chen, Yuan‐Soon Ho, Hsiu-O Ho, Shyr-Yi Lin, Kuo‐Hsiang Chuang, Ming‐Thau Sheu

Drug Delivery · 2018 · 27 citations · 23 references

DOIFull text

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Concepts

Abstract

MDDs and actively targeted tumors with a drug cargo to enhance drug accumulation in tumors leading to greater antitumor activity against antigen-positive tumors.

References

23

Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology

Stefan Tenzer, Dominic Docter, Jörg Kuharev et al. · Nature Nanotechnology · 2013 · 2.2K citations

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Dynasore, a Cell-Permeable Inhibitor of Dynamin

Eric Macia, Marcelo Ehrlich, Ramiro Massol et al. · Developmental Cell · 2006 · 2K citations · Full text

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Nanoparticles in cancer therapy and diagnosis

Irène Brigger, Catherine Dubernet, Patrick Couvreur · Advanced Drug Delivery Reviews · 2012 · 946 citations

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Different endocytotic uptake mechanisms for nanoparticles in epithelial cells and macrophages

D. Kühn, Dimitri Vanhecke, Benjamin Michen et al. · Beilstein Journal of Nanotechnology · 2014 · 499 citations · Full text

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Search for inhibitors of endocytosis

Dipannita Dutta, Julie G. Donaldson · Cellular Logistics · 2012 · 435 citations · Full text

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