Concepedia

HLA-DQ Mismatching and Kidney Transplant Outcomes

Napat Leeaphorn, J Peña, Natanong Thamcharoen, Eliyahu V. Khankin, Martha Pavlakis, Francesca Cardarelli

Clinical Journal of the American Society of Nephrology · 2018 · 69 citations · 23 references

DOIFull text

Open access

Abstract

HLA-DQ mismatching is associated with lower graft survival independent of HLA-ABDR in living donor kidney transplants and deceased donor kidney transplants with cold ischemia time ≤17 hours, and a higher 1-year risk of acute rejection in living and deceased donor kidney transplants.

References

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, , +12

Class II HLA Epitope Matching—A Strategy to Minimize De Novo Donor-Specific Antibody Development and Improve Outcomes

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De Novo DQ Donor-Specific Antibodies Are Associated With a Significant Risk of Antibody-Mediated Rejection and Transplant Glomerulopathy

Michelle Willicombe, Paul Brookes, Ruhena Sergeant et al. · Transplantation · 2012 · 245 citations