Palladium‐Catalyzed <i>ortho</i> C−H Arylation of Benzaldehydes Using <i>ortho</i>‐Sulfinyl Aniline as Transient Auxiliary

Abstract

A Pd^II -catalyzed ortho-(Csp² )-H arylation reaction of benzaldehydes using a catalytic amount of 2-(methylsulfinyl)aniline as transient auxiliary was developed. This reaction is compatible with a broad range of benzaldehyde and aryl iodide substrates. Compared with other related reaction systems, an excellent regioselectivity for ortho-C(sp² )-H bonds over benzylic C(sp³ )-H bonds was obtained for ortho-alkyl-benzaldehyde substrates.