Concepedia

CSA-90 Promotes Bone Formation and Mitigates Methicillin-resistant Staphylococcus aureus Infection in a Rat Open Fracture Model

Rebecca Mills, Tegan L. Cheng, Kathy Mikulec, Lauren Peacock, David Isaacs, Carl Genberg, Paul B. Savage, David G. Little, Aaron Schindeler

Clinical Orthopaedics and Related Research · 2018 · 13 citations · 19 references

DOIFull text

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Abstract

The antimicrobial properties of CSA-90 combined with further evidence of its proosteogenic potential make it a promising compound to develop further for orthopaedic applications.

References

19

Insights on Evolution of Virulence and Resistance from the Complete Genome Analysis of an Early Methicillin-Resistant <i>Staphylococcus aureus</i> Strain and a Biofilm-Producing Methicillin-Resistant <i>Staphylococcus epidermidis</i> Strain

Steven R. Gill, Derrick E. Fouts, Gordon L. Archer et al. · Journal of Bacteriology · 2005 · 1K citations · Full text

Production of a standard closed fracture in laboratory animal bone

Frank Bonnarens, Thomas A. Einhorn · Journal of Orthopaedic Research® · 1984 · 902 citations

Human Host Defense Peptide LL-37 Prevents Bacterial Biofilm Formation

Joerg Overhage, Andrea Campisano, Manjeet Bains et al. · Infection and Immunity · 2008 · 671 citations · Full text

The management of open fractures.

Ramon B. Gustilo, Robert L. Merkow, David C. Templeman · Journal of Bone and Joint Surgery · 1990 · 659 citations

, , +4

Factors Influencing Infection Rate in Open Fracture Wounds

Michael J. Patzakis, Jeanette Wilkins · Clinical Orthopaedics and Related Research · 1989 · 637 citations

, , +16