Red-emissive azabenzanthrone derivatives for photodynamic therapy irradiated with ultralow light power density and two-photon imaging

Qiguang Zang, Jiayi Yu, Wenbin Yu, Jun Qian, Rongrong Hu, Ben Zhong Tang

Chemical Science · 2018 · 65 citations · 27 references

DOIFull text

Open access

Concepts

Abstract

, this compound demonstrates significant photo-induced cytotoxicity toward HeLa cells. Moreover, deep tissue penetration can be realized by two-photon imaging of mouse brain vessels with these azabenzanthrone derivatives at vertical depths of up to 280 μm, attributed to the large emission wavelength and efficient emission.

References

27