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Efficacy and Renal Safety of Dapagliflozin in Patients with Type 2 Diabetes Mellitus Also Receiving Metformin: A Real-Life Experience

Alessandro Scorsone, Gabriella Saura, Mattia Fleres, Lucia Spanò, Vito Aiello, Davide Brancato, Anna Di Noto, Francesca Provenzano, Vincenzo Provenzano

Journal of Diabetes Research · 2018 · 12 citations · 14 references

DOIFull text

Open access

Abstract

Dapagliflozin is effective and safe in patients with T2D also receiving metformin. Glycemic control was already achieved with dapagliflozin + metformin, and add-on therapy was not associated with further improvements.

References

14

Management of Hyperglycemia in Type 2 Diabetes, 2015: A Patient-Centered Approach: Update to a Position Statement of the American Diabetes Association and the European Association for the Study of Diabetes

Silvio E. Inzucchi, Richard M. Bergenstal, John B. Buse et al. · Diabetes Care · 2014 · 3K citations

, , +18

Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: a randomised, double-blind, placebo-controlled trial

Clifford J. Bailey, Jorge Luiz Gross, Anne Pieters et al. · The Lancet · 2010 · 848 citations

, , +6

Dapagliflozin Monotherapy in Type 2 Diabetic Patients With Inadequate Glycemic Control by Diet and Exercise

Ele Ferrannini, Silvia Ramos, Afshin Salsali et al. · Diabetes Care · 2010 · 700 citations · Full text

Sodium-Glucose Cotransport Inhibition With Dapagliflozin in Type 2 Diabetes

James F. List, Vincent Woo, Enrique Morales et al. · Diabetes Care · 2008 · 689 citations · Full text

The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose.

Y. Kanai, W S Lee, Dennis Brown et al. · Journal of Clinical Investigation · 1994 · 619 citations · Full text

, , +20