Case Reports in Dermatology · 2018 · 24 citations · 5 references
MedicineDermatologyPharmacotherapyAllergyDermatopathologyHypersensitivityInflammatory DermatosesInflammatory Skin DiseasesInflammatory Skin DisordersDermatologic DisordersDermatologic PharmacologyFollicular HyperkeratosisInterleukin Inhibitor TherapyPalmoplantar PsoriasisPityriasis Rubra PilarisPsoriasis ImmunopathologyPsoriatic Disease
Pityriasis rubra pilaris is an inflammatory dermatologic disorder of unknown cause and often confounded with psoriasis. It is characterised by hyperkeratotic follicular papules, scaly erythematous plaques, palmoplantar keratoderma, and a progression to generalised erythroderma. Here, we report the case of a 68-year-old man with pityriasis rubra pilaris, who was successfully treated with ixekizumab, an interleukin-17A inhibitor.
5
W.A.D. Griffiths · Clinical and Experimental Dermatology · 1980 · 353 citations
Interleukin 23–Helper T Cell 17 Axis as a Treatment Target for Pityriasis Rubra Pilaris
Laurence Feldmeyer, Alessio Mylonas, Olivier Demaria et al. · JAMA Dermatology · 2017 · 121 citations · Full text
Medicine, Dermatology, Immunology +17