Concepedia

The transcription factor SKN-1 and detoxification gene ugt-22 alter albendazole efficacy in Caenorhabditis elegans

Pauline Fontaine, Keith Choe

International Journal for Parasitology Drugs and Drug Resistance · 2018 · 24 citations · 44 references

DOIFull text

Open access

Concepts

Abstract

by 2.3-2.5-fold. The influence of a nematode UGT on albendazole efficacy is consistent with recent studies demonstrating glucose conjugation of benzimidazoles.

References

44

MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0

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Global numbers of infection and disease burden of soil transmitted helminth infections in 2010

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Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans

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Developmental genetics of the mechanosensory neurons of Caenorhabditis elegans

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