Hyponatremia and activation of vasopressin secretion are both independently associated with 30‐day mortality: results of a multicenter, observational study

Abstract

This prospective study including medical patients upon emergency room admission found hyponatremia as well as an activation of the vasopressin system to be independently associated with mortality. This suggests that stress- and vasopressin-independent mechanisms are responsible for the association of low sodium levels with mortality.