Droplet digital <scp>PCR</scp> for <scp>BCR</scp>/<scp>ABL</scp>(P210) detection of chronic myeloid leukemia: A high sensitive method of the minimal residual disease and disease progression

Abstract

In contrast with RT-qPCR, dd-PCR is more sensitive, thus enabling accurate conversion of dd-PCR results into internationally standard RT-qPCR results by conversion equation, to achieve a deeper molecular biology-based stratification of BCR/ABL(P210) MRD. It has some reference value to monitor disease progression in clinic.