Down‐regulation of natural resistance‐associated macrophage protein‐1 (Nramp1) is associated with 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP)/1‐methyl‐4‐phenylpyridinium (MPP⁺)‐induced α‐synuclein accumulation and neurotoxicity

Abstract

These data suggest that the neuronal expression of Nramp1 is important for protecting against the development of MPTP/MPP⁺ -induced α-synuclein pathology and neurotoxicity.