Engineering of E. coli inherent fatty acid biosynthesis capacity to increase octanoic acid production

Abstract

This work demonstrates the effectiveness of integration of computational strain design and experimental characterization as a starting point in rewiring metabolism for octanoic acid production. This result in conjunction with the results of other studies using OptForce in strain design demonstrates that this strategy may be also applicable to engineering <i>E. coli</i> for other customized bioproducts.