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Proof of concept study of an apoptosis-signal regulating kinase (ASK1) inhibitor (selonsertib) in combination with an acetyl-CoA carboxylase inhibitor (GS-0976) or a farnesoid X receptor agonist (GS-9674) in NASH

MedicineReceptor Tyrosine KinaseApoptosisApoptosis-signal Regulating KinaseCell DeathAcetyl-coa Carboxylase InhibitorMechanism Of ActionPharmacotherapyConcept StudyAnti-cancer AgentPharmacologyCell BiologyCell SignalingCancer ResearchDrug Discovery