Association of Neutrophil-to-Lymphocyte Ratio With Mortality and Cardiovascular Disease in the Jackson Heart Study and Modification by the Duffy Antigen Variant

Abstract

Neutrophil-to-lymphocyte ratio was prospectively associated with all-cause mortality, CHD, and HF, with closer median time to event diagnoses in the JHS. Furthermore, the Duffy antigen variant locus was associated with a lower baseline NLR and modified the mortality, CHD, stroke, and HF associations.