Pemphigoid gestationis successfully treated with intravenous immunoglobulin

Abstract

Pemphigoid gestationis (PG), also known as <i>herpes gestationis</i>, is a rare autoimmune blistering disease specific to pregnancy, which usually presents in the second or third trimesters and, in 15%-25% of cases, during the immediate postpartum period.¹Although the ethiopathogeny of PG is not fully clarified, most patients develop antibodies against a 180 kDa transmembrane hemidesmosomal protein (BP180; BPAG2; collagen XVII).² PG has a strong association with human leucocyte antigens DR3 and DR4.³We report a case of a 29-year-old female patient with PG successfully treated with intravenous immunoglobulin.