Direct synthesis of alkenyl iodides<i>via</i>indium-catalyzed iodoalkylation of alkynes with alcohols and aqueous HI

Abstract

A convenient and efficient indium-catalyzed approach to synthesize alkenyl iodides has been developed through direct iodoalkylation of alkynes with alcohols and aqueous HI under mild conditions. This catalytic protocol offers an attractive approach for the synthesis of a diverse range of alkenyl iodides in good to excellent yields.