Ultrastructural Alteration of Pulmonary Capillary Endothelial Glycocalyx During Endotoxemia

Abstract

It appears that endothelial glycocalyx in the lung is markedly disrupted under experimental endotoxemia conditions. This finding supports the notion that disruption of the glycocalyx is causally related to the microvascular endothelial dysfunction that is characteristic of sepsis-induced ARDS.