VEGF-A regulates sFlt-1 production in trophoblasts through both Flt-1 and KDR receptors

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

Sharon E. Maynard, Jiang-Yong Min, Jaime R. Merchan et al. · Journal of Clinical Investigation · 2003 · 4K citations · Full text

Medicine, Maternal Health, Obstetrics +17

A study of placental bed spiral arteries and trophoblast invasion in normal and severe pre‐eclamptic pregnancies

J. W. Meekins, Robert Pijnenborg, M. Hanssens et al. · BJOG An International Journal of Obstetrics & Gynaecology · 1994 · 912 citations

Medicine, Gynecology, Obstetrics +15

Corneal avascularity is due to soluble VEGF receptor-1

Balamurali K. Ambati, Miho Nozaki, Nirbhai Singh et al. · Nature · 2006 · 681 citations · Full text

Medicine, Ophthalmology, Surgery +14

Vascular Endothelial Growth Factor Ligands and Receptors That Regulate Human Cytotrophoblast Survival Are Dysregulated in Severe Preeclampsia and Hemolysis, Elevated Liver Enzymes, and Low Platelets Syndrome

Yan Zhou, Michael McMaster, Kirstin Woo et al. · American Journal Of Pathology · 2002 · 644 citations · Full text

Public Health, Maternal Health, Obstetrics +17

Elevated Placental Soluble Vascular Endothelial Growth Factor Receptor-1 Inhibits Angiogenesis in Preeclampsia

Shakil Ahmad, Asif Ahmed · Circulation Research · 2004 · 515 citations · Full text

Life Sciences, Maternal Health, Obstetrics +17