Apelin/APJ expression in the heart and kidneys of hypertensive rats

Isolation and Characterization of a Novel Endogenous Peptide Ligand for the Human APJ Receptor

Kazuhiko Tatemoto, Masaki Hosoya, Yugo Habata et al. · Biochemical and Biophysical Research Communications · 1998 · 1.7K citations

Medicine, Medicinal Chemistry, Pharmacology +10

A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11

Brian F. O’Dowd, Michael Heiber, Audrey Chan et al. · Gene · 1993 · 840 citations

Life Sciences, Genetics, Molecular Genetics +5

The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism

Kazuhiko Tatemoto, Kiyoshige Takayama, Iku Kumaki et al. · Regulatory Peptides · 2001 · 643 citations

Medicine, Cardiology, Physiology +14

Apelin, the Novel Endogenous Ligand of the Orphan Receptor APJ, Regulates Cardiac Contractility

István Szokodi, Pasi Tavi, Gábor Földes et al. · Circulation Research · 2002 · 617 citations

Life Sciences, Pharmacology, Physiology +11

Molecular properties of apelin: tissue distribution and receptor binding

Yuji Kawamata, Yugo Habata, Shoji Fukusumi et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2001 · 515 citations

Medicine, Biochemistry, Pharmacology +10