Concepedia

Publication | Open Access

Phosphodiesterase‐5 inhibition potentiates cerebrovascular reactivity in chronic traumatic brain injury

DOIFull Paper Access

23

Citations

35

References

2018

Year

Kimbra Kenney, Franck Amyot, Carol Moore, Margalit Haber, L. Christine Turtzo, Christian Shenouda, Erika Silverman, Yunhua Gong, Bao Xi Qu, Leah Harburg,
Annals of Clinical and Translational Neurology

Abstract

Single-dose sildenafil improves regional CVR deficits in chronic TBI patients. CVR and ΔCVR are potential predictive and pharmacodynamic biomarkers of PDE5 inhibitor therapy for TCVI. Sildenafil is a potential therapy for TCVI.

References

YearCitations

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