Boosting phagocytosis and anti‐inflammatory phenotype in microglia mediates neuroprotection by PPARγ agonist MDG548 in Parkinson's disease models - Concepedia

Concepedia

Publication | Open Access

Boosting phagocytosis and anti‐inflammatory phenotype in microglia mediates neuroprotection by PPARγ agonist MDG548 in Parkinson's disease models

DOI Full Paper Access

59

Citations

49

References

2018

Year

Daniela Lecca, Elżbieta Janda, Giovanna Mulas, Andrea Diana, Concetta Martino, Fabrizio Angius, Stefano Spolitu, Maria Antonietta Casu, Gabriella Simbula, Laura Boi,

British Journal of Pharmacology

Abstract

This study adds a novel mechanism for PPARγ-mediated neuroprotection in PD and suggests that increasing phagocytic activity and anti-inflammatory markers may represent an effective disease-modifying approach.

References

	Year	Citations

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