Aminocatalytic Privileged Diversity‐Oriented Synthesis (ApDOS): An Efficient Strategy to Populate Relevant Chemical Spaces

Abstract

Diversity‐oriented synthesis and aminocatalysis constitute two important tools for access to important compounds. The extraordinary development in these two areas has allowed chemists to populate new regions in chemical space. As a consequence, new libraries of complex and diverse frameworks are becoming available for drug discovery. ApDOS is presented as a new concept that shows the scope of aminocatalysis for the synthesis and diversification of privileged structures.