Reperfusion of the rat brain tissues following acute ischemia: the correlation among diffusion-weighted imaging, histopathology, and aquaporin-4 expression.

Abstract

There is a close correlation between AQP4 expression and the cerebral intracellular edema. The change of ADC values may indirectly reflect the level of the AQP4 expression. DWI may become a promising, noninvasive imaging modality to predict early stroke and reperfusion injury.