Association of Human Immunodeficiency Virus Infection and Risk of Peripheral Artery Disease

Abstract

Infection with HIV is associated with a 19% increased risk of PAD beyond that explained by traditional atherosclerotic risk factors. However, for those with sustained CD4 cell counts <200 cells/mm³, the risk of incident PAD events is nearly 2-fold higher whereas for those with sustained CD4 cell counts ≥500 cells/mm³ there is no excess risk of incident PAD events compared with uninfected people.