Concepedia

Comparative studies on the human serum albumin binding of the clinically approved EGFR inhibitors gefitinib, erlotinib, afatinib, osimertinib and the investigational inhibitor KP2187

Orsolya Dömötör, Karla Pelivan, Attila Borics, Bernhard K. Keppler, Christian R. Kowol, Éva A. Enyedy

Journal of Pharmaceutical and Biomedical Analysis · 2018 · 30 citations · 29 references

Concepts

MedicineOncologyPharmacologyCancer PharmacologyClinical PharmacologyMolecular PharmacologyEnzyme InhibitionProtein BindingTyrosine Kinase InhibitorsAlbumin AdsorptionEgfr InhibitionEpidermal Growth Factor Receptor InhibitionErlotinib TherapyPlasma Albumin

References

29

SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling

Nicolas Guex, Manuel C. Peitsch · Electrophoresis · 1997 · 11.3K citations

Life Sciences, Biochemistry, Bioinformatics +7

Atomic structure and chemistry of human serum albumin

Xiao He, Daniel C. Carter · Nature · 1992 · 3.8K citations

Life Sciences, Biochemistry, Chemistry +12

Structural Basis of the Drug-binding Specificity of Human Serum Albumin

J. Ghuman, Patricia A. Zunszain, I. Petitpas et al. · Journal of Molecular Biology · 2005 · 1.9K citations

Life Sciences, Biochemistry, Pharmaceutics +12

Tyrosine kinase – Role and significance in Cancer

Manash K. Paul, A.K. Mukhopadhyay · International Journal of Medical Sciences · 2004 · 617 citations · Full text

Medicine, Cancer Biology, Oncology +16

Subdomain IB Is the Third Major Drug Binding Region of Human Serum Albumin: Toward the Three-Sites Model

Ferenc Zsila · Molecular Pharmaceutics · 2013 · 377 citations

Medicine, Biochemistry, Pharmacology +13