Ruthenium‐Catalyzed Selective C−C Coupling of Allylic Alcohols with Free Indoles: Influence of the Metal Catalyst

Abstract

Versatile reactive activities of allyl alcohols with free indoles in C-H functionalization reactions were investigated. Direct alkylation or cascade cyclization reactions could be selectively controlled based on the catalyst system: Ru(PPh₃ )₃ Cl₂ provided C3-substituted β-ketone indoles whereas [Ru(p-cymene)Cl₂ ]₂ yielded cyclized indoles.