Comparison of detergent‐based decellularization protocols for the removal of antigenic cellular components in porcine aortic valve

Abstract

These results indicated that SDS-based protocols more effectively removed antigenic cellular components compared to Triton X-100-based protocols. These results are clinically significant because complete removal of antigenic determinants is critical to decrease adverse immune-mediated and inflammatory responses to a PAV when used in xenogeneic application.