Predictive Value of Malignancy of Thyroid Nodule Ultrasound Classification Systems: A Prospective Study

Abstract

Classification systems had elevated predictive value of malignancy in high-risk classes. ATA and AACE/ACE/AME systems were effective for ruling out indication to FNA in low-US-risk nodules. A similar diagnostic accuracy and a substantial interobserver agreement was provided by the three- and the five-category classifications.