Nuclear and membrane estrogen receptor antagonists induce similar <scp>mTORC</scp>2 activation‐reversible changes in synaptic protein expression and actin polymerization in the mouse hippocampus

Abstract

nERs and mER contribute similarly to the changes in proteins and structures associated with synaptic plasticity, and mTORC2 may be a novel target of hippocampal-dependent dementia such as Alzheimer's disease as proposed by previous studies.