Association between biofilm production, adhesion genes and drugs resistance in different SCCmec types of methicillin resistant <i>Staphylococcus aureus</i> strains isolated from several major hospitals of Iran.

Abstract

OBJECTIVES: The ability of bacteria to produce biofilm and adhesion makes them more resistant to antibiotics. The current study aims to evaluate the biofilm formation by Staphylococcus aureus and to determine the prevalence of adhesion genes, also their correlation with drug resistance. MATERIALS AND METHODS: genes were determined by PCR technique. Biofilm formation was studied by microtiter plate assay, the clonal relations of the strains were examined by SCCmec and Spa typing. RESULTS: >0.05). Frequency of All virulent genes in type III SCCmec was higher than other types. CONCLUSION: genes are correlated with biofilm production.