Dicer1 Deficiency in the Idiopathic Pulmonary Fibrosis Fibroblastic Focus Promotes Fibrosis by Suppressing MicroRNA Biogenesis - Concepedia

Concepedia

Publication | Closed Access

Dicer1 Deficiency in the Idiopathic Pulmonary Fibrosis Fibroblastic Focus Promotes Fibrosis by Suppressing MicroRNA Biogenesis

62

Citations

34

References

2018

Year

Jeremy Herrera, Daniel Beisang, Mark S. Peterson, Colleen L. Forster, Adam Gilbertsen, Alexey O. Benyumov, Karen Smith, Christopher E. Korenczuk, Victor H. Barocas, Kacey L. Guenther,

American Journal of Respiratory and Critical Care Medicine

Abstract

Our data identify suppression of fibroblast Dicer1 expression in the myofibroblast-rich IPF fibroblastic focus core as a central step in the mechanism by which the ECM sustains fibrosis progression in IPF.

References

	Year	Citations

Page 1