Effects of 1,25-dihydroxyvitamin D₃on the differentiation of MC3T3-E1 osteoblast-like cells

Abstract

We suggest that 1,25-dihydroxyvitamin D₃ positively affects cell differentiation and matrix mineralization. Therefore, it may function as a stimulating factor in osteoblastic bone formation and can be used as an additive in bone regeneration treatment.