PAS‐C platelets contain less plasma protein, lower anti‐A and anti‐B titers, and decreased HLA antibody specificities compared to plasma platelets

Abstract

Decreased plasma proteins likely underlie lower rates of allergic and febrile, nonhemolytic transfusion reactions from the infusion of PAS-C PLTs. Decreased anti-A and anti-B titers may prevent hemolysis from minor ABO mismatch. Lower HLA antibody specificities may mitigate transfusion-related acute lung injury.