Clinical Interventions in Aging · 2018 · 15 citations · 34 references
Our results indicate that placebo analgesia is influenced by age, with older individuals showing larger placebo analgesia than young adults. Although these results should be confirmed in clinical pain populations, the current observations bear potentially important consequences for the design of future placebo-controlled trials and for healthcare professionals working with elderly patients.
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Defining the clinically important difference in pain outcome measures
John T. Farrar, Russell K. Portenoy, Jesse A. Berlin et al. · Pain · 2000 · 1.1K citations
Activation of the Opioidergic Descending Pain Control System Underlies Placebo Analgesia
Falk Eippert, Ulrike Bingel, Eszter Schoell et al. · Neuron · 2009 · 831 citations · Full text