Acute Heart Failure Following Myocardial Infarction: Complement Activation Correlates with the Severity of Heart Failure in Patients Developing Cardiogenic Shock

Abstract

Complement activation discriminated cardiogenic shock from non-shock in acute ST-elevation myocardial infarction complicated by HF and correlated with regional contractility and endothelial cell activation, suggesting a pathogenic role of complement in this condition.