Isoflurane anesthesia in aged mice and effects of A1 adenosine receptors on cognitive impairment

Chunlong Zuo, Chun‐Man Wang, Jin Liu, Ting Shen, Jiang‐Ping Zhou, Xinrui Hao, Yizhao Pan, Hua‐Cheng Liu, Qingquan Lian, Han Lin

CNS Neuroscience & Therapeutics · 2018 · 33 citations · 41 references

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Abstract

We found an association between isoflurane exposure, impairment of spatial memory, decreasing level of NR2B, and increasing levels of A-beta and P-tau, presumably via the activation of the A1A receptor.

References

41