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Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial Hypertension

DOIFull Paper Access

104

Citations

37

References

2018

Year

Olivier Boucherat, Thibaut Peterlini, Alice Bourgeois, Valérie Nadeau, Sandra Breuils‐Bonnet, Stéphanie Boilet-Molez, François Potus, Jolyane Meloche, Sophie Chabot, Caroline Lambert,
American Journal of Respiratory and Critical Care Medicine

Abstract

Our data show for the first time that accumulation of mtHSP90 is a feature of PAH-PASMCs and a key regulator of mitochondrial homeostasis contributing to vascular remodeling in PAH.

References

YearCitations

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