Concepedia

Publication | Closed Access

Modulation of Micro RNA Expression and Osteoblast Differentiation by Nanotopography

DOI

29

Citations

0

References

2018

Year

Elisa Mattias Sartori, Osvaldo Magro Filho, Daniela Baccelli Silveira Mendonça, Xiang Li, Jianping Fu, Gustavo Mendonça
The International Journal of Oral & Maxillofacial Implants

Abstract

Surfaces with nanotopography have the potential to improve the osseointegration response in order to reduce the osseointegration time and also increase bone formation around the implants, improving areas with low bone quality. Within the limitation of this study, nanotopography surfaces affected MSC differentiation to osteoblasts. Several miRNAs were differentially regulated by surface topography. These miRNAs could be related to the differentiation response to help control the osseointegration process.