Enantioselective Synthesis of <i>trans</i>‐Vicinal Diamines <i>via</i> Rhodium‐Catalyzed [2+2] Cycloaddition of Allenamides

Abstract

Abstract An efficient protocol for the enantioselective Rh‐catalyzed intermolecular head‐to‐head [2+2] cycloaddition of allenamides was developed. A variety of enantio‐enriched cyclobutane‐1,2‐diamine derivatives were achieved in good yields with good to excellent enantioselectivities. magnified image