Concepedia

hsa-mir183/EGR1–mediated regulation of E2F1 is required for CML stem/progenitor cell survival

Francesca Pellicano, Laura Park, Lisa Hopcroft, Mansi M. Shah, Lorna Jackson, Mary T. Scott, Cassie J. Clarke, Amy Sinclair, Sheela A. Abraham, Alan Hair,

Blood · 2018 · 46 citations · 51 references

DOIFull text

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Concepts

Abstract

/EGR1-mediated E2F1 regulation and demonstrate this axis as a novel, critical factor for CML SPC survival, offering new insights into leukemic stem cell eradication.

References

51

Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

Yoav Benjamini, Yosef Hochberg · Journal of the Royal Statistical Society Series B (Statistical Methodology) · 1995 · 108.7K citations

, , +13

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha et al. · Proceedings of the National Academy of Sciences · 2005 · 56.7K citations · Full text

, , +12

Gene Ontology: tool for the unification of biology

Michael Ashburner, Catherine A. Ball, Judith A. Blake et al. · Nature Genetics · 2000 · 44.6K citations · Full text

, , +9

Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments

Gordon K. Smyth · Statistical Applications in Genetics and Molecular Biology · 2004 · 12K citations

, , +13

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

Rafael A. Irizarry · Biostatistics · 2003 · 10.7K citations · Full text

, , +14