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Nicotine induces apoptosis in human osteoblasts via a novel mechanism driven by H2O2 and entailing Glyoxalase 1-dependent MG-H1 accumulation leading to TG2-mediated NF-kB desensitization: Implication for smokers-related osteoporosis

Health SciencesMedicineSmokers-related OsteoporosisPhysiologyNicotineNicotine Induces ApoptosisCell DeathPharmacologyCell BiologyOsteoporosisBone MetabolismOsteocalcinOxidative StressTg2-mediated Nf-kb Desensitization