Large-Cell Neuroendocrine Carcinoma of the Lung: A Focused Analysis of <i>BRAF</i> Alterations and Case Report of a <i>BRAF</i> Non-V600–Mutated Tumor Responding to Targeted Therapy

Abstract

Although uncommon, L-LCNEC does seem to contain activating and therefore actionable alterations. We thus highlight the value of pursuing next-generation sequencing for patients with this disease.