PGE<sub>2</sub>/EP<sub>4</sub> receptor attenuated mucosal injury via β‐arrestin1/Src/EGFR‐mediated proliferation in portal hypertensive gastropathy - Concepedia

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PGE<sub>2</sub>/EP<sub>4</sub> receptor attenuated mucosal injury via β‐arrestin1/Src/EGFR‐mediated proliferation in portal hypertensive gastropathy

DOI Full Paper Access

20

Citations

27

References

2017

Year

Siwei Tan, Xiaoliang Chen, Minyi Xu, Xiaoli Huang, Huiling Liu, Jie Jiang, Yu Lu, Xiaojie Peng, Bin Wu

British Journal of Pharmacology

Abstract

These results indicate that β-arr1 regulates PGE<sub>2</sub> /EP<sub>4</sub> receptor-mediated mucosal proliferation by promoting activation of the Src/EGFR/Akt/PCNA signalling pathway, and thus, this network is a potential therapeutic target for PHG.

References

	Year	Citations

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