An Outbreak of NDM-1-Producing <i>Klebsiella pneumoniae</i> , Associated with OmpK35 and OmpK36 Porin Loss in Tunisia

Abstract

This study describes an outbreak of NDM-1-producing K. pneumoniae strains, isolated from a Tunisian hospital, caused by two clones belonging to ST147 and ST307; and highlights the role of OMPs loss, in combination with β-lactamase expression, in conferring high carbapenem resistance.