Antifeedant effect of polygodial and drimenol derivatives against <scp><i>Spodoptera frugiperda</i></scp> and <i>Epilachna paenulata</i> and quantitative structure‐activity analysis

Abstract

The results suggest that drimanic compounds have potential as new agents against S. frugiperda and E. paenulata. A quantitative structure-activity relationship (QSAR) analysis of the whole series, supported by electronic studies, suggested that drimanic compounds have structural features necessary for increasing antifeedant activity, namely a C-9 carbonyl group and an epoxide at C-8 and C-9. © 2018 Society of Chemical Industry.