The natural compound, formononetin, extracted from <scp><i>Astragalus membranaceus</i></scp> increases adipocyte thermogenesis by modulating PPARγ activity

Abstract

Taken together, our study demonstrates that the Chinese herbal medicine from A. membranaceus and its constituent formononetin have the potential to reduce obesity and associated metabolic disorders. Our results suggest that formononetin regulates adipocyte thermogenesis as a non-classical PPARγ agonist.