Altered low-frequency oscillation amplitude of resting state-fMRI in patients with discogenic low-back and leg pain

Abstract

Our results revealed widespread abnormalities in ALFF in the pain matrix and information-processing regions as well as a decrease in ALFF in the DMN. These results open up an important new avenue to better understand the nature of the link between intrinsic activity and peripheral pain and sensory impairment in discogenic LBLP patients.