Nano-graphene oxide composite for in vivo imaging

Abstract

The radiochemical safety of ¹⁸F-nGO-PEG was measured by a reactive oxygen species and cell viability test. The biodistribution of ¹⁸F-nGO-PEG could be observed easily by PET, which suggested the significantly high sensitivity tumor uptake of ¹⁸F-nGO-PEG and in a tumor bearing CT-26 mouse compared to the control. ¹⁸F-nGO-PEG was applied successfully as an efficient radiotracer or drug agent in vivo using PET imaging. This article is expected to assist many researchers in the fabrication of ¹⁸F-labeled graphene-based bio-conjugates with high reproducibility for applications in the biomedicine field.